Nancy Glazier began painting with oils at the age of eight and sold her first painting at 12. At age 16, her family moved to Cody, Wyoming, on the edge of Yellowstone Park and she studied basic painting techniques with Adolf Spohr, the Cody Museum muralist. Glazier began supporting herself by the sales of her paintings at the age of 18. She gained a greater understanding of animals at the anatomy institute Zahourek Systems where she took Equine Anatomy, an intensive study of animal structural systems.
Glazier is a great pet lover, but prefers to paint wild animals. She travels to numerous natural parks and wildlife preserves to sketch and photograph animals in their natural environments. She attempts to depict all the characteristics of a site, such as the chill of winter, the fresh smell of pine, or the soft light of dusk as she creates a relationship between this environment and the animal. Glazier's says, "I choose to put all the detail in the faces of the animals I paint, because my emphasis is on portraying the mood and the moment in that particular animal's life. I strive to capture that animal on that day in a certain light, and in a certain circumstance. Each animal I paint is unique."
The Collector's Society awarded Glazier the Wildlife Artist of the year in 1992 and her paintings have been incorporated into many private collections and museums, including the Museum of Church History and Art in Salt Lake City, the Hiram Blauvelt Art Museum, and the National Museum of Wildlife Art.